Bilirubin is a superior biomarker for hepatocellular carcinoma diagnosis and for differential diagnosis of benign liver disease
Objectives To develop a novel diagnostic model combining bilirubin, protein induced by vitamin K absence or antagonist-II (PIVKA-II), and alpha-fetoprotein (AFP) to improve hepatocellular carcinoma (HCC) diagnosis. Methods The serum levels of PIVKA-Ⅱ, AFP, and...
The predictive value of the C-reactive protein/albumin ratio in adult patients with complicated appendicitis
Objectives The purpose of this study was to analyze the role of C-reactive protein/albumin ratio (CRP/ALB) in the diagnosis of complicated appendicitis in adults. Methods A retrospective analysis of 202 patients with acute appendicitis admitted to the Emergency...
Diagnostic accuracy of stool sample-based PCR in detecting Helicobacter pylori infection: a meta-analysis
Abstract The present study was to evaluate the diagnostic accuracy of different types of PCR tests with the aim of determining which one performs best for detecting Helicobacter pylori in stool samples. Related articles were searched from PubMed,...
Laborleitertreffen Brandenburg, Berlin, Mecklenburg-Vorpommern, Sachsen-Anhalt 2023
Es war ein kleines Jubiläum:
Das 30. (!) Laborleitertreffen fand unter der Leitung und wissenschaftlichen Organisation von Frau Professor Dr. S. Westphal (Dresden), Herrn Dr. T. Ansorge (Magdeburg), Herrn Prof. Dr. F. Bühling (Dresden), Herrn Dr. L. Briedigkeit (Schwerin), Herrn PD Dr. K. H. Reuner (Cottbus) sowie Herrn Dr. K.-G. Heinze (Berlin) in Potsdam statt.
Vor rund 70 Teilnehmern moderierten Frau Prof. Dr. Westphal, Herr Prof. Dr. Bühling sowie Herr Dr. Briedigkeit den ersten Tag des Treffens, am zweiten Tag führten Herr Dr. Ansorge sowie Herr Dr. Heinze durch die Veranstaltung. Die Landesärztekammer Brandenburg honorierten die Teilnahme am Laborleitertreffen mit 7 Fortbildungspunkten.
Anwendertreffen LC-MS/MS
Das 21. LC-MS/MS Anwendertreffen findet vom 07.–08. Dezember im Kloster Banz, Bad Staffelstein statt. Die Anmeldung ist bis zum 15.10.2023 geöffnet. Weitere Details finden Sie hier:Link zu: Weitere Details Link zu: Einladungsschreiben Copyright Bild: Reinhold Möller,...
Assessment of antibody titer and side effects after fourth doses of COVID-19 mRNA vaccination in 38 healthy volunteers
Objectives Fourth dose of SARS-CoV-2 vaccination was started from the end of May, 2022 in Japan. However, data on the precise analysis of the side effects after fourth vaccination, remain scarce. Here, we examined the side effects and the levels of SARS-CoV-2 antibody...
Applied biostatistics in laboratory medicine
As Associate Editors of J Lab Med, we were pleased to organize a special issue on “Applied Biostatistics in Laboratory Medicine” at the request of Editor-in-Chief Peter Schuff-Werner. This field is both old and new for the journal. On the one hand, biostatistical...
Statistical learning and big data applications
The amount of data generated in the field of laboratory medicine has grown to an extent that conventional laboratory information systems (LISs) are struggling to manage and analyze this complex, entangled information (“Big Data”). Statistical learning, a generalized...
Comparison of three indirect methods for verification and validation of reference intervals at eight medical laboratories: a European multicenter study
Objectives Indirect methods for the indirect estimation of reference intervals are increasingly being used, especially for validation of reference intervals, as they can be applied to routine patient data. In this study, we compare three statistically different...
A visualization tool for continuous reference intervals based on GAMLSS
Reference intervals are an important component in the interpretation of medical laboratory findings. Especially in children and adolescents, their limits sometimes can change very rapidly with age. We suggest continuous methods to better represent the age-dependent...
