A new approach to the interpretation of B-type natriuretic peptide concentration in children with congenital heart disease
Objectives BNP is the unique cardiac marker that reflects not as much as the degree of heart muscle damage, but mostly the severity of hemodynamic disorder, which is important in congenital heart disease. The only disadvantage of this marker is the barely studied...
Prof. Kohse für weitere Amtszeit als Schatzmeister der EFLM wiedergewählt
Am Rande der EuroMedLab 2023 in Rom wurden auf dem General Meeting der EFLM die Mitglieder des Executive Boards 2024/2025 gewählt. Prof. Dr. Dr. Klaus Kohse erhielt die Mehrheit der Stimmen für eine weitere Amtszeit als Schatzmeister. Wir gratulieren Herrn Prof. Kohse...
Medical operational AI: artificial intelligence in routine medical operations
Despite substantial gains facilitated by Artificial Intelligence (AI) in recent years, it has to be applied very cautiously in sensitive domains like medicine due to the lack of explainability of many methods in this field. We aim to provide a system to overcome these...
Performance evaluation of cobas pure integrated solutions at multiple sites in Europe and Asia
Objectives We evaluated analytical performance, functionality, reliability, and comparability of cobas® pure integrated solutions (Roche Diagnostics) under routine-like conditions. Methods The study was conducted in Europe and Asia (five sites). Seventy-six...
Using Shiny apps for statistical analyses and laboratory workflows
Abstract In many areas of healthcare, digitization has progressed only slowly so far. The SARS-CoV-2 pandemic in particular has shown how valuable software solutions that are deployable at short notice, can be. In this review we present some selected possibilities of...
EDTA-associated pseudothrombocytopenia: definition and real-world occurrence
Objectives To better characterize occurrence and extent of anticoagulant-associated pseudothrombocytopenia (PTCP) in the daily routine of a high-throughput clinical laboratory in order to draw conclusions on a more precise definition of this phenomenon. Methods...
Predictive value of C-reactive protein-to-albumin ratio for risk of 28-day mortality in patients with severe pneumonia
Objectives To explore the predictive value of C-reactive protein (CRP)-to-albumin (ALB) ratio (CAR) for the risk of 28-day mortality in patients with severe pneumonia. Methods A total of 152 patients with severe pneumonia treated from January 2020 to January 2022 were...
Elevated plasma interleukin 21 is associated with higher probability and severity of idiopathic membranous nephropathy
Objectives Interleukin 21 (IL-21) is a receptor participating in innate immunity and correlates with the activation of innate immune cells. We sought to investigate the role of plasma IL-21 in patients with idiopathic membranous nephropathy (IMN). Methods This was a...
Differences in venous, capillary and interstitial glucose concentrations in individuals without diabetes after glucose load
Objectives Differences between capillary and venous glucose concentrations have been reported in the past. In continuous glucose monitoring (CGM) system performance studies, comparator measurements are often performed in venous samples, despite CGM systems...
Digital competence in laboratory medicine
Objectives Even though most physicians and professionals in laboratory medicine have received basic training in statistics, experience shows that a general understanding of data analysis is not yet available on a broad scale. Therefore, data literacy, data-driven...
